Furan-2-ylmagnesium bromide
2-furylmagnesium bromide
CAS: 98754-48-4
Molecular Formula: C4H3BrMgO
Furan-2-ylmagnesium bromide - Names and Identifiers
| Name | 2-furylmagnesium bromide |
| Synonyms | 2-furylmagnesium bromide (2-Furanyl)bromomagnesium Bromo(2-furanyl) magnesium (2-Furyl) magnesium bromide Furan-2-ylmagnesium bromide |
| CAS | 98754-48-4 |
Furan-2-ylmagnesium bromide - Physico-chemical Properties
| Molecular Formula | C4H3BrMgO |
| Molar Mass | 171.28 |
Furan-2-ylmagnesium bromide - Introduction
2-furylmagnesium bromide is an organic compound with the chemical formula C5H5BrMgO. It is a colorless to pale yellow liquid, soluble in ether and organic solvents.
2-furylmagnesium bromide is mainly used for the synthesis of carbonyl compounds in organic synthesis. It can be used as a Grignard reagent to undergo a substitution reaction with carbonyl compounds to produce the corresponding alcohols or ethers. This reaction has a wide range of applications in the synthesis of natural products and pharmaceuticals.
The method for preparing 2-furylmagnesium bromide is generally reacting 2-furylbromide with magnesium metal in an anhydrous environment. The reaction is usually carried out in ether or dichloromethane as solvent at low temperature. After the progress of the reaction, the reaction solution may be neutralized by treatment with an acid or water vapor to obtain the target product.
Safety information on the use of 2-furylmagnesium bromide. Due to its characteristics of metal organic compounds, it needs to be safe during operation and storage. It is highly corrosive and should avoid contact with skin and eyes. Wear appropriate protective gloves and goggles. In addition, it is also a flammable substance and should avoid contact with oxygen and avoid open flames. During use, it should be carried out in a well-ventilated environment and avoid inhaling its vapor.
2-furylmagnesium bromide is mainly used for the synthesis of carbonyl compounds in organic synthesis. It can be used as a Grignard reagent to undergo a substitution reaction with carbonyl compounds to produce the corresponding alcohols or ethers. This reaction has a wide range of applications in the synthesis of natural products and pharmaceuticals.
The method for preparing 2-furylmagnesium bromide is generally reacting 2-furylbromide with magnesium metal in an anhydrous environment. The reaction is usually carried out in ether or dichloromethane as solvent at low temperature. After the progress of the reaction, the reaction solution may be neutralized by treatment with an acid or water vapor to obtain the target product.
Safety information on the use of 2-furylmagnesium bromide. Due to its characteristics of metal organic compounds, it needs to be safe during operation and storage. It is highly corrosive and should avoid contact with skin and eyes. Wear appropriate protective gloves and goggles. In addition, it is also a flammable substance and should avoid contact with oxygen and avoid open flames. During use, it should be carried out in a well-ventilated environment and avoid inhaling its vapor.
Last Update：2024-04-09 21:54:55
